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中国胆囊癌发病率及流行趋势分析

Analysis of the incidence and epidemic trend of gallbladder cancer in China

摘要:

许多临床医师对胆囊癌的发病率及流行趋势存在以下4种误区:(1)胆囊及肝外胆管癌的发病率就是胆囊癌的发病率.(2)胆囊癌是消化系统常见的恶性肿瘤.(3)胆囊癌是胆道系统最常见的恶性肿瘤.(4)胆囊癌的发病率逐年升高.以国家癌症中心(NCCR)最新发布的《2016中国肿瘤登记年报》为基础,结合历年的年报和相关文献中有关胆囊及肝外胆管癌发病率的数据,辅以临床数据,分析中国胆囊癌的发病率为(1.00~1.30)/10万,提出胆囊癌不是消化系统和胆道系统最常见的恶性肿瘤,胆囊癌的发病率近年来也并无明显升高,其5年相对生存率自2003年以来平均每个时间段降低0.9%.胆囊癌虽然发病率低,但是恶性程度高,预后差,凸显了目前对该病缺乏有效的治疗手段,进一步提示加强胆囊癌早诊断、早治疗的必要性.

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abstracts:

Many clinicians have the following 4 misconceptions about the incidence and epedemil trend of gallbladder cancer.(1) The incidence of gallbladder cancer and extrahepatic bile duct carcinoma is considered as the incidence of gallbladder cancer.(2) The gallbladder cancer is the common malignant tumor of the digestive system.(3) The gallbladder cancer is the most common malignant tumor of biliary tract system.(4) The incidence of gallbladder cancer is increasing year by year.Based on the latest annual report of the 2016 Chinese Cancer Registry Annual Report,published by the National Cancer Center (NCCR),combined with previous annual reports and the data of the incidence of gallbladder and extrahepatic bile duct cancer in the related articles,supplemented by clinical data,the author points out that the incidence of gallbladder cancer in China is about 1.00-1.30 per 100 000.It is pointed out that gallbladder cancer is not the most common cancer in the digestive and biliary systems.The incidence of gallbladder cancer has not been significantly increased in recent years,and its 5-year relative survival rate has been reduced by 0.9% since 2003.Although the incidence of gallbladder cancer is low,the malignant degree is high and the prognosis is poor.It highlights the lack of effective treatment for the disease,and further hints that we should strengthen the necessity of early diagnosis and treatment of gallbladder cancer.

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