Combined treatment promotes the long-range axon regeneration to right brain targets

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摘要Axons in the peripheral nervous system (PNS) can regenerate after injury. However, the adult mammalian central nervous system (CNS) loses the intrinsic regrowth ability. No robust axon regeneration occurs spontaneously after nerve injury, which was clearly observed by Ramon y Cajal in the early 20th century (1,2). Due to lack of regenerative potentials, the injured axons permanently lose their connections from their targets, e.g. in the optic nerve damage and spinal cord injury. Later, pioneer studies found peripheral nerve segments can bridge the injured axons in the rodent retina (3), medulla and spinal cord (4). The transected axons are able to regrow along the peripheral nerve"bridge".

作者单位 Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China ^[1] School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China;St. John's College, The University of Hong Kong, Hong Kong, China ^[2]

栏目名称

Editorial

DOI 10.3978/j.issn.1000-4432.2017.01.06

发布时间 2017-05-27

基金项目

This editorial review was supported by National Natural Science Foundation of China [31600839]（B14036）； Guangdong Innovative and Entrepreneurial Research Team Program [2013S046]； Shenzhen Peacock Plan (B.P.). Also supported by Funds of Leading Talents of Guangdong [2013] and Program of Introducing Talents of Discipline to Universities

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准确一般字义偏差语意偏离译文作用小提交