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目的 探讨复方去氧孕烯治疗子宫腺肌病的临床疗效.方法 对42例子宫腺肌病患者于月经第1天开始服用复方去氧孕烯片,每次1片,每日1次,连续21 d.停7 d后开始下一个周期,共6个周期.观察用药前后月经量、血红蛋白及子宫体积变化,采用视觉模糊评分法(VAS)进行痛经评分.结果 服用复方去氧孕烯治疗6个月后疼痛明显减轻,评分由原来(8.51±1.73)分降至(0.62±0.70)分,P<0.01;经量减少,血红蛋白治疗前为(104.71±12.09)g/L,治疗6个月后为(112.00±8.57)g/L,P<0.01;治疗6个月后子宫体积稍缩小,但不明显(P>0.05).结论 复方去氧孕烯治疗子宫腺肌病近期疗效显著,且价廉、方便.

Objective To evaluate the efficacy of Marvelon on treatment of adenomyosis.Methods A total of 42 women with adenomyosis were recruited in the study.They were given Marvelon on the first day of menstruation,1 piece,qd,continouly for 21 days.With an alternation of seven days a new cycle begins.There are 6 cycles in total.We observe their degree of dysmenorrheal,menstrual blood volume(MBV) ,hemoglobin and the volume of uterus before and after Marvelon used.Results After 6 months,the dysmenorrheal remitted obviously,the score decline from (8.51±1.73 ) to (0.62±0.70) ,P <0.01.The MBV reduced and hemoglobin rise distinctly ,before treatment Hb is (104.71±12.09) while (112.00±8.57)after therapy,P <0.01.After treatment the volume of uterus shrinks a little, but not significant(P > 0.05).Conclusion Marvelon is an effective drug in treatment of adenomyosis in the near future,and is cheap,convcnieat.