宫颈环形电切术与阴道镜下活检在诊断宫颈上皮内瘤样变价值比较
Comparison of LEEP biopsy and colposcopical biopsy in the diagnosis of CIN
目的 探讨宫颈环形电切术(LEEP)术后病检与阴道镜下活检在诊断宫颈上皮内瘤样变(CIN)中的临床意义.方法 对妇科门诊阴道镜下诊断为CIN患者130例,再行LEEP术,比较其病理结果的差异.结果 阴道镜下活检结果CIN Ⅰ级、CINⅡ级、CINⅢ级(不包括原位癌)与LEEP术后病检结果符合率分别为55.26%、66.10%、78.79%,总符合率为66.15%.阴道镜下活检对诊断CINⅢ级的准确性要高于CIN Ⅰ级和CINⅡ级,但两者相比较差异无显著性(P0.05).结论 阴道镜下活检可取得对宫颈病变首次的病理结果,具有局限性;而LEEP可弥补阴道镜下活检的缺陷,在明确诊断CIN中,LEEP术与阴道镜下活检可互为补充,且有治疗作用.
更多Objective To compare the diagnostic clinical significance between loop electrosurgical excision procedure (LEEP) and colposcopical biopsy for cervical intracpithelial neoplasia(CIN). Methods 130 cases of pa-tients diagnosed as CIN under colposcopical biopsy were treated by LEEP in court of gynecology clinic. The conven-tional pathologic diagnosis was recorded in all conization specimens. Results The coincidence rate between colpo-scopical biopsy and LEEP biopsy in CIN Ⅰ, CIN Ⅱ, CIN Ⅲ (not comprised carcinoma in situ) was 55.26%,66.10% ,78.79% respectively;The total coincidence rate was 66.15%. The accuracy of colposcopic biopsy for diag-nosing CINⅢ was higher than that for CIN Ⅰ and CIN Ⅱ,but there was no statistical difference. Conclusion Colpo-scopical biopsy for cervical lesions can be achieved for the frist time the results of pathology, have limitations. LEEP biopsy can compensate partially the deficiency of colposcopic biopsy. In a dear diagnosis of CIN, LEEP biopsy and colposcopical biopsy may complement each other, and achieve thcrpeutic effects.
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