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目的 调查某医院儿内科多重耐药菌感染情况,为儿科抗生素合理使用提供参考指导.方法 回顾性调查分析2009-2011年某医院儿内科591例住院患者多重耐药菌感染情况.结果 2009-2011年三年间多重耐药菌感染率差异无统计学意义(x2=0.028,P=0.986).在591例患者中,17例发生多重耐药菌感染,感染率2.87％,主要来源于社区(82.4％)；64.7％的感染发生在呼吸道,感染菌以肺炎克雷伯菌和大肠埃希菌为主(58.8％),出现多重耐药菌感染前均使用过抗菌药物.结论 儿内科多重耐药菌的感染与滥用抗菌药物及不合理用药有关,应加强监测及管理.

Objective To investigate the multidrug-resistant bacteria infection in pediatrics of our hospital and guide the rational usage of antibiotic,Methods The retrospective survey method was adopted to analyze the multidrug-resistant bacteria infection of 591 patients in paediatrics from 2009 to 2011.Results There were no statistical differences of multidrug resistance bacteria infection rates in the three years (x2 =0.028,P =0.986).Among 591 patients,17 patients were with multidrug-resistant bacteria infection,the positive rate was 2.87％,82.4％ origin of society area,64.7％ was respiratory tract infection,58.8％ resistance bacteria including Klebsiella pneumoniae and Escherichia coli,appear multidrug resistance bacteria infection previous all used antibiotic drugs.Conclusion The multidrug resistance bacteria infection is related to occur in paediatrics abuse and unrationaly use of antibiotics.Its should be strengthened to supervise and manage.