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乳腺癌患者早期保乳手术疗效观察

Clinical effect of breast-conserving surgery on early breast cancer patients

摘要:

目的 探讨乳腺癌患者早期保乳手术的临床疗效.方法 对128例保乳手术的乳腺癌早期患者自手术当天开始计算,随访30 ~ 80个月,中位随访时间64个月,统计治疗结果及术后美容效果.结果 随访率为100%,总生存率为95.30%,1年生存率为100.00%(128/128),3年生存率为98.44%(126/128),5年生存率为95.31%(122/128).术后随访死亡6例,3例死于肝转移,2例死于肺转移,l例死于非肿瘤原因.局部复发率2.34%(3/128),腋淋巴结复发率1.56%(2/128).复发时间平均为术后3年2个月,远处转移率3.91%(5/128).术后128例保乳患者美容评价,优71例(55.47%),良55例(42.97%),差2例(1.56%).患者接受度为98%.结论 保乳手术解决了女性对美的追求,提高了患者生存质量.

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Objective To explore the clinical efficacy of early breast cancer patients underwent breast-conserving surgery with postoperative chemotherapy and radiotherapy.Methods A retrospective analysis of 128 early breast cancer patients underwent routine breast-conserving surgery was conducted.The clinical effect and cosmetic results were analyzed by the follow-up results of 128 cases.Results (1) The 5-year follow-up rate was 100%,overall survival rate was 95.3%,1-year survival rate was 100% (128/128) ;3-year survival rate was 98.4% (126/128) ;5-year survival rate was 95.30% (122/128).Postoperative follow-up 6 patients died,3 patients died of liver metastases,2 patients died of lung metastases,1 patient died of non-cancerous reasons.The local recurrence rate was 2.34% (3/128),axillary lymph node recurrence rate was 1.56% (2/128).The average recurrence time was three years and two months after operation,distant metastasis rate was 3.91% (5/128).(2) Beauty evaluations of 128 patients with breast-conserving surgery were excellent in 71 cases (55.5%),good in 55 cases (43.0%),and poor'in 2 cases (1.6%).Good,acceptable as acceptance criteria,the acceptance rate was 98%.Conclusion Breast-conserving surgery is not only to a certain extent to solve the pursuit of female beauty,but also improve their quality of life.But only the complete elimination of residual lesions in order to truly ensure that no recurrence of tumor.Therefore,the appropilate survival rate of patients for radiotherapy and chemotherapy can be extended so that the patient's breast to maintain a good shape.Breast-conserving surgery combined with radiotherapy and chemotherapy is superior to the modified radical surgery,and popularization in the hospital.

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