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目的 分析老年人复发卵巢癌的临床病理特点及对预后的影响.方法 140例老年卵巢癌患者按复发情况将卵巢癌复发患者103例归为观察组,将其余卵巢癌未复发患者37例归为对照组,比较两组患者首次入院后癌组织病理特点,并分析观察组患者复发入院后癌组织病理特点,综合分析两组老年卵巢癌患者预后情况与其临床病理特点.结果 观察组癌组织分期中处低分化的患者数和病理分期在处M的患者数均明显高于对照组(x2=13.48、15.87,均P＜0.05).除中枢神经毒性外,观察组不良反应发生率明显高于对照组(x2 =13.8、11.6、14.5、13.9、14.9、13.4,均P＜0.05).结论 老年卵巢癌的临床病理特点在一定程度上可以反映患者预后情况,对于患者病情的复发和预后评定有一定临床价值.

Objective To discuss and analyze clinical pathological characteristics of senile recurrent ovarian cancer and its influences on prognosis.Methods 140 senile ovarian cancer patients who have been admitted in ourhospital were selected as study subjects.103 cases with recurrent ovarian cancer were selected as observation group (group A),and the rest 37 cases who did not suffer from recurrent ovarian cancer were selected as control group(group B).Pathological characteristics of carcinoma tissues after their first admission in our hospital were compared between the two groups.And pathological characteristics of carcinoma tissues of group A after their second admissionin our hospital were analyzed,comprehensively analyzed prognosis situations and clinical pathological characteristics of patients in these two groups.Results In group A,the number of poorly differentiated carcinoma tissues was obviouslymore than group B,and the number of patients whose neoplasm staging was M stage was more than that in group B,the differences between the two groups were significant (x2 =13.48,15.87,all P ＜ 0.05).The incidence rate of adverse reactions between the two groups also had statistical significance(x2 =13.8,11.6,14.5,13.9,14.9,13.4,all P ＜0.05).Conclusion The clinical pathological characteristics of senile recurrent ovarian cancer can reflect patients'prognosis situations in some degree,and has certain clinical value in evaluation of patients' disease recurrence and prognosis.