• 医学文献
  • 知识库
  • 评价分析
  • 全部
  • 中外期刊
  • 学位
  • 会议
  • 专利
  • 成果
  • 标准
  • 法规
  • 临床诊疗知识库
  • 中医药知识库
  • 机构
  • 作者
热搜词:
换一批
论文 期刊
取消
高级检索

检索历史 清除

医学文献 >>
  • 全部
  • 中外期刊
  • 学位
  • 会议
  • 专利
  • 成果
  • 标准
  • 法规
知识库 >>
  • 临床诊疗知识库
  • 中医药知识库
评价分析 >>
  • 机构
  • 作者
热搜词:
换一批

龙血竭联合腺苷钴胺治疗中老年人带状疱疹疗效观察

Clinical efficacy of Longxuejie joint cobamamide in the treatment of elderly patients with herpes zoster

摘要:

目的:探讨龙血竭联合腺苷钴胺治疗中老年人带状疱疹的疗效。方法选择104例中老年带状疱疹患者为研究对象,根据随机数字表法分为治疗组和对照组,两组均同时口服泛昔洛韦250 mg,每天3次,共14 d;肌内注射腺苷钴胺500 mg,每天1次,14 d为1个疗程。治疗组加用龙血竭肠溶片4片,每天3次口服,疗程14 d。比较两组疗效及后遗神经痛情况。结果治疗组痊愈34例,显效13例,总有效率为90.4%,显著高于对照组的73.1%,差异有统计学意义(χ2=5.216,P<0.05)。治疗组水疱消失、疼痛缓解、完全结痂及痊愈时间均显著短于对照组,差异均有统计学意义(t=3.216、5.432、4.643、3.654,均P<0.05)。治疗组无后遗神经痛发生,对照组后遗神经痛发生率为13.5%,两组差异具有统计学意义(χ2=4.875,P<0.05)。结论在带状疱疹的治疗中,龙血竭联合腺苷钴胺具有良好的疗效,可以显著改善患者临床症状,起效快,后遗神经痛发生率低,具有很高的临床应用价值。

更多
abstracts:

Objective To investigate the clinical efficacy of cobamamide combined with Longxuejie in the treatment of herpes zoster in the elderly .Methods 104 elderly patients with herpes zoster were randomly divided into the treatment group and the control group .Both the two groups were given orally famciclovir 250mg,3 times a day for 14 days,intramuscularly injected gland glycosides cobalamin 500mg,1 day,14 days a course of treatment ,the treat-ment group was given Longxuejie enteric-coated tablets 4,3 times a day orally for 14 days.The blisters disappeared , pain relief,and recovery time of completely crusted ,treatment efficacy and neuralgia were compared between the two groups.Results In the treatment group,34 cases were cured,effective in 13 cases,total effective rate was 90.4%, which was significantly higher than 73.1% in the control group,the difference was statistically significant (χ2 =5.216,P<0.05).The blisters disappeared,pain relief,and recovery time of completely crusted in the treatment group were significantly shorter than those in the control group (t =3.216,5.432,4.643,3.654,all P <0.05).No postherpetic neuralgia was observed in the treatment group ,the incidence rate of postherpetic neuralgia of the control group was 13.5%,the difference was statistically significant (χ2 =4.875,P<0.05).Conclusion The Longxuejie combined with cobamamide in the treatment of herpes zoster in elderly patients has reliable effect ,fast improvement of clinical symptoms,a low incidence of postherpetic neuralgia ,it is worthy of clinical application .

More
作者: 王红 [1]
期刊: 《中国基层医药》2014年19期 2963-2964页 ISTIC
栏目名称: 论著
DOI: 10.3760/cma.j.issn.1008-6706.2014.19.033
发布时间: 2014-09-11
  • 浏览:180
  • 下载:36

加载中!

相似文献

  • 中文期刊
  • 外文期刊
  • 学位论文
  • 会议论文

加载中!

加载中!

加载中!

加载中!

扩展文献

特别提示:本网站仅提供医学学术资源服务,不销售任何药品和器械,有关药品和器械的销售信息,请查阅其他网站。

  • 客服热线:4000-115-888 转3 (周一至周五:8:00至17:00)

  • |
  • 客服邮箱:yiyao@wanfangdata.com.cn

  • 违法和不良信息举报电话:4000-115-888,举报邮箱:problem@wanfangdata.com.cn,举报专区

官方微信
万方医学小程序
new翻译 充值 订阅 收藏 移动端

官方微信

万方医学小程序

使用
帮助
Alternate Text
调查问卷