玻璃酸钠关节腔注射配合口服阳和汤治疗膝骨关节炎的疗效分析
Analysis of therapeutic effect of sodium hyaluronate intra-articular injection combined with oral Yanghe decoction in the treatment of knee osteoarthritis
目的 探讨玻璃酸钠关节腔注射配合口服阳和汤治疗膝骨关节炎的疗效.方法 将80例膝骨关节炎患者采用随机数字表法分为两组,每组40例.对照组患者给予玻璃酸钠关节腔注射,研究组患者则加服阳和汤,比较两组患者中医症状评分、膝关节指标、总体治疗效果与生活质量.结果 研究组患者治疗后中医症状总分为(7.08±1.18)分,显著低于对照组的(10.42±2.01)分(t=9.063,P<0.01);研究组治疗后疼痛视觉模拟评分和骨关节炎指数评分分别为(1.48±0.59)分、(19.10±3.08)分,均显著低于对照组的(3.70±1.12)分、(23.40±3.56)分(t=11.091、5.777,均P<0.01);研究组治疗后膝关节功能评分为(83.04±10.49)分,显著高于对照组的(71.81±9.67)分(t=4.978,P<0.01);研究组治疗6个月后生理机能、生理职能、躯体疼痛、精神健康与精力评分均显著高于对照组(t=5.190、8.535、4.569、3.266、6.694,均P<0.01);研究组显效率和总有效率分别为72.5%、95.0%,均明显高于对照组的50.0%、77.5%,差异均有统计学意义(χ2=4.266、5.165,均P<0.05).结论 玻璃酸钠关节腔注射配合口服阳和汤治疗膝骨关节炎的疗效显著.
更多Objective To investigate the curative effect of sodium hyaluronate intraperitoneal injection combined with oral Yanghe decoction in the treatment of knee osteoarthritis .Methods 80 patients with knee osteoar-thritis were randomly divided into two groups ,40 cases in each group .The control group was given intra -articular injection of sodium hyaluronate ,and the study group was treated with Yanghe decoction in addition .The TCM symptom score , knee joint index , overall treatment effect and quality of life were compared between the two groups .Results The total score of TCM symptoms after treatment in the study group was (7.08 ±1.18)points,which was significantly lower than (10.42 ±2.01)points in the control group(t=9.063,P<0.01).The VAS score and WOMAC score after treatment in the study group were (1.48 ±0.59)points,(19.10 ±3.08)points,respectively,which were significantly lower than (3.70 ±1.12)points and (23.40 ±3.56)points in the control group (t=11.091,5.777,all P<0.01). The HSS score after treatment in the study group was (83.04 ±10.49) points,which was significantly higher than (71.81 ±9.67)points in the control group(t =4.978,P<0.01).The physiological function,physical function, physical pain,mental health and energy scores after 6 months treatment in the study group were significantly higher than those in the control group (t=5.190,8.535,4.569,3.266,6.694,all P<0.01).The effective rate and total effective rate of the study group were 72.5%and 95.0%,respectively,which were significantly higher than those of the control group(50.0%,77.5%),the differences were statistically significant (χ2 =4.266,5.165,all P<0.05). Conclusion Sodium hyaluronate injection combined with oral Yanghe decoction is effective in the treatment of knee osteoarthritis.
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