产妇血、乳汁与婴儿血微量元素水平及相关性分析
The levels and correlation analysis of trace elements in maternal blood, breast milk and infant blood
目的 分析产妇血、乳汁及婴儿血微量元素水平及相关性.方法 收集250例自然分娩产妇产后42 d血、乳汁及其婴儿血为标本,采用原子吸收光谱法测定其中所含的钙(Ca)、铁(Fe)、锌(Zn)、镁(Mg)与铜(Cu)的含量,并分析产妇血、乳汁与婴儿血微量元素相关性.结果 除产妇血钙与婴儿血钙水平差异无统计学意义(P>0.05)外,产妇血、乳汁及婴儿血中Ca、Fe、Zn、Mg、Cu水平两两比较差异均有统计学意义(P<0.05);产妇血与婴儿血中Ca、Fe水平均呈正相关[Ca(r=0.221,P=0.047)、Fe(r =0.107,P=0.043)];产妇乳汁与婴儿血中Fe水平呈正相关(r=0.139,P=0.035);产妇血与其乳汁中Ca、Fe、Zn、Cu微量元素均呈正相关[Ca(r=0.016,P=0.007)、Fe(r =0.143,P=0.022)、Zn(r =0.162,P=0.019)、Cu(r =0.274,P=0.013)].结论 产后42 d妇女血微量元素与乳汁微量元素水平形成梯度,使乳汁维持微量元素一定比例,有助于婴儿的微量元素的吸收,与其生长发育密切相关,故定期测定孕期、产后妇女及婴儿微量元素水平,指导产妇平衡膳食,提倡母乳喂养,及时科学补充微量元素量,可早期预防婴儿早期钙、铁、锌等微量元素的缺乏.
更多Objective To investigate the correlation of trace elements in maternal blood,breast milk and infant blood.Methods Atomic absorption spectrographic method was used to measure blood and milk trace elements [calcium (Ca),ferrum (Fe),zinc (Zn),magnesium (Mg),copper(Cu)] of maternal of natural delivery and infant in 250 cases,then to analyze the correlation of trace elements in maternal blood,breast milk and infant blood in postpartum 42 days.Results There were statistically significant differences in trace elements between the maternal blood,breast milk and infant blood (P < 0.05).There was a positive correlation of Ca,and Fe between maternal blood and infant blood [Ca (r =0.221,P =0.047),Fe (r =0.107,P =0.043)];Fe had a positive correlation between breast milk and infant blood (r =0.139 P =0.035);There was a positive correlation of the trace elements between maternal blood and milk,but no correlation in Mg.Conclusions There was the gradient of trace elements in maternal blood and breast milk in postpartum 42 days.It can keep breast milk in a certain percentage of trace element and contribute to absorption of trace elements and growth and development in infant.The regular determination of trace elements during pregnancy and postpartum in women and their infant can direct a balanced diet and advocate breastfeeding.It can also prevent the lack of calcium,iron,zinc and other trace elements in infant.
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