吲哚菁绿分子荧光影像技术在腹腔镜肝切除术中的应用进展
Indocyanine green fluorescent imaging in laparoscopic hepatectomy
笔者检索web of science、Pubmed和万方、中国知网数据库中有关吲哚菁绿分子荧光影像技术应用于肝切除,尤其是腹腔镜肝切除的文献,并行归纳总结,以综述吲哚菁绿分子荧光影像技术在腹腔镜肝切除术中的应用现状及不足.吲哚菁绿分子荧光影像技术在腹腔镜肝切除术中的应用目前主要集中于:(1)肿瘤识别、定位及切缘界定;(2)肝段染色;(3)胆道辨识及胆漏检测.目前其主要的临床应用不足为肿瘤识别假阳性率高、探测深度有限和吲哚菁绿使用剂量及间隔时间需个体化处理.所以,吲哚菁绿分子荧光影像技术在腹腔镜肝切除中具有广阔的应用前景,但其技术细节及长期肿瘤学效果如何尚需进一步完善和研究.
更多The literatures on indocyanine green fluorescent imaging in hepatectomy,especially in laparoscopic hepatectomy were reviewed by retriving Web of science,Pubmed,China National Knowledge Infrastructure (CNKI) and Wanfang database.To view the progress and limitations of indocyanine green fluorescent imaging in laparoscopic hepatectomy.Indocyanine green fluorescent imaging can:(1) effectively detect and differentiate tumor;(2) visualize the staining of liver segment and differentiate bile duct;(3) detect bile leakage.However,high false positive rate and limitation in depth in tumor detectation are still the major disadvantages of indocyanine green fluorescent imaging.Also,the best dose and interval of indocyanine green are unknown.Indocyanine green fluorescent imaging will be very usefull in laparoscopic hepatectomy in future,also need to be explored in details,especially in oncology effect.
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