• 医学文献
  • 知识库
  • 评价分析
  • 全部
  • 中外期刊
  • 学位
  • 会议
  • 专利
  • 成果
  • 标准
  • 法规
  • 临床诊疗知识库
  • 中医药知识库
  • 机构
  • 作者
热搜词:
换一批
论文 期刊
取消
高级检索

检索历史 清除

医学文献 >>
  • 全部
  • 中外期刊
  • 学位
  • 会议
  • 专利
  • 成果
  • 标准
  • 法规
知识库 >>
  • 临床诊疗知识库
  • 中医药知识库
评价分析 >>
  • 机构
  • 作者
热搜词:
换一批

Selective impairment of musical emotion recognition in patients with amnesic mild cognitive impairment and mild to moderate Alzheimer disease

摘要:

Background:Patients with Alzheimer disease (AD) and amnesic mild cognitive impairment (aMCI) have deficits in emotion recognition.However,it has not yet been determined whether patients with AD and aMCI also experience difficulty in recognizing the emotions conveyed by music.This study was conducted to investigate whether musical emotion recognition is impaired or retained in patients with AD and aMCI.Methods:All patients were recruited from the First Affiliated Hospital of Anhui Medical University between March 1,2015 and January 31,2017.Using the musical emotion recognition test,patients with AD (n =16),patients with aMCI (n =19),and healthy controls (HCs,n =16) were required to choose one of four emotional labels (happy,sad,peaceful,and fearful) that matched each musical excerpt.Emotion recognition scores in three groups were compared using one-way analysis of variance (ANOVA) test.We also investigated the relationship between the emotion recognition scores and Mini-Mental State Examination (MMSE) using Pearson's correlation analysis test in patients with AD and aMCI.Results:Compared to the HC group,both of the patient groups showed deficits in the recognition of fearful musical emotions (HC:7.88 ± 1.36;aMCI:5.05 ± 2.34;AD:3.69 ± 2.02),with results of a one-way ANOVA confirming a significant main effect of group (F(2,50) =18.70,P < 0.001).No significant differences were present among the three groups for the happy (F(2,50)=2.57,P =0.09),peaceful (F(2,50) =0.38,P =0.09),or sad (F(2,50) =2.50,P =0.09) musical emotions.The recognition of fearful musical emotion was positively associated with general cognition,which was evaluated by MMSE in patients with AD and aMCI (r =0.578,P < 0.001).The correlations between the MMSE scores and recognition of the remaining emotions were not significant (happy,r =0.228,P =0.11;peaceful,r =0.047,P =0.74;sad,r =0.207,P =0.15).Conclusion:This study showed that both patents with AD and aMCI had decreased ability to distinguish fearful emotions,which might be correlated with diminished cognitive function.

更多
作者单位: Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China [1] Department of Neurology, The First People's Hospital of Jiujiang, Jiujiang, Jiangxi 332000, China [2] Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China;Collaborative Innovation Centre of Neuropsychiatric Disorders and Mental Health, Hefei, Anhui 230032, China;Department of Medical Psychology, Anhui Medical University, Hefei, Anhui 230032, China [3]
期刊: 《中华医学杂志(英文版)》2019年132卷19期 2308-2314页 SCIMEDLINEISTICCSCDBP
栏目名称: Original Articles
DOI: 10.1097/CM9.0000000000000460
发布时间: 2019-11-19
基金项目:
grants from the National Natural Science Foundation of China Anhui Provincial Natural Science Foundation
翻译满意度评价:
提交
  • 浏览:12
  • 下载:8

加载中!

相似文献

  • 中文期刊
  • 外文期刊
  • 学位论文
  • 会议论文

加载中!

加载中!

加载中!

加载中!

特别提示:本网站仅提供医学学术资源服务,不销售任何药品和器械,有关药品和器械的销售信息,请查阅其他网站。

  • 客服热线:4000-115-888 转3 (周一至周五:8:00至17:00)

  • |
  • 客服邮箱:yiyao@wanfangdata.com.cn

  • 违法和不良信息举报电话:4000-115-888,举报邮箱:problem@wanfangdata.com.cn,举报专区

官方微信
万方医学小程序
new翻译 充值 订阅 收藏 移动端

官方微信

万方医学小程序

使用
帮助
Alternate Text
调查问卷