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目的 探讨自体富血小板血浆对难愈合创面的辅助治疗效果.方法 难愈合创面患者15例,其中男11例,女4例.糖尿病性溃疡6例,外伤手术后溃疡创面5例,压疮4例.创面清创后使用自体富血小板凝胶涂抹创面,每周换药,定期检测创面细菌培养结果,观察肉芽生长情况.待创面情况允许时,行植皮或皮瓣转移手术封闭创面.结果 15例患者中3例换药自行愈合,4例经皮瓣转移手术后愈合,8例植皮后愈合.所有患者均无复发或窦道产生.结论 自体富血小板凝胶可以有效促进创面生长,改善创面情况,提高了手术封闭创面的成功率.

Objective To investigate the effects of autologous platelet-rich plasma in the treatment of refractory wound.Methods Fifteen cases with refactory wound ( 1 1 males and 4 females) involving six cases with diabetic ulcer,five with post-surgical ulcer wounds and four with pressure sore were enrolled into the study.The autologous platelet-rich gel was applied to the wounds after debridement and dressing change was done every week.The results of wound bacterial culture were regularly detected and the growth of granulation was observed.Skin graft or flap graft surgery was performed to close the wound when the wound condition was permitted.Results Of all,three patients had spontaneous healing after the change of dressing,four got healing after flap graft and eight attained healing after skin graft.There was no recurrence or sinus after treatment.Conclusion Autologous platelet-rich gel accelerates wound healing,improves wound condition,and raises success rate of surgical closure of the wound.