摘要目的:探讨IBA Proteus Plus质子治疗系统旋转机架(GTR 360°)笔形束扫描(PBS)专用治疗头的束流性能并进行验收测试，评估PBS的束流特性以确保其满足临床治疗精确性、安全性的要求。方法:根据验收测试要求，PBS束流测试项主要包括：积分深度剂量(IDD)参数测试；最大、最小射程处辐射野测试；机架角度射野一致性及其束斑特性测试；单野横向平面剂量均匀性测试；单野纵向平面剂量均匀性测试；机器跳数重复性和线性测试。结果:所测最大射程精度偏差为0.03 g/cm 2，最大能量回调精度偏差为0.01 g/cm 2，最大后缘剂量跌落偏差为0.078 g/cm 2。最大、最小射程能量的最大射野分别为30.2 cm×40.2 cm、30.1 cm×40.1 cm。不同机架角和射程测量中特定图形计划的通过率最低为97%。中心束斑 x、 y轴向偏差最大值分别为-0.16、-0.21 mm，对称性最差值为0.8%；其他束斑 x、 y轴向最大尺寸偏差分别为0.11、0.14 mm，最大位置精度偏差分别为0.60、0.43 mm。单野横向平面剂量均匀性， x、 y轴向高能区最大值分别为0.55%、0.80%；低能区最大值分别为0.6%、0.75%。单野纵向平面高能区剂量均匀性为0.79%，低能区剂量均匀性为2.22%。机器跳数重复性因子为0.106%，线性偏差最大值为0.67%。 结论:PBS专用治疗机头通过了所有束流性能验收测试，满足了各项参数要求，整个束流系统具有较高的精确性、重复性以及较好的稳定性。

abstractsObjective:To explore the beam performance of GTR 360° PBS dedicated nozzle for IBA Proteus Plus proton system and evaluate the beam characteristics of PBS during acceptance test procedure (ATP) to meet the precision and safety requirements of clinical treatment.Methods:According to the requirements of acceptance tests, the beam tests of PBS mainly included: test of integrated depth dose (IDD), test of maximum field size at the maximum and minimum ranges, field uniformity and informative PBS tests for the GTR 360°, test of lateral dose uniformity in a single field uniform dose in a cube, test of longitudinal dose uniformity in a single field uniform dose in a cube, and test of monitor unit reproducibility and proportionality.Results:The maximum deviation measured of range, fall back accuracy and distal fall-off was 0.03 g/m 2, 0.01 g/m 2 and 0.078 g/m 2, respectively. Maximum field size at the maximum and minimum ranges was 30.2 cm×40.2 cm and 30.1 cm×40.1 cm, respectively. During the different gantry angles and ranges, the lowest γ passing rate of a pattern plan was 97%, the maximum deviation of the centrical beam spot size at the X and Y axes was -0.16 mm and -0.21 mm, and the worst symmetry was 0.80%. Compared with the centrical beam spot, the maximum size deviation of the other beam spots was 0.11 mm and 0.14 mm at the X and Y axes, and the maximum position accuracy deviation of the beam spot was 0.60 mm and 0.43 mm at the X and Y axes. The maximum deviation of lateral dose uniformity at at the X and Y axes was 0.55% and 0.80% in the high energy region, and 0.6% and 0.75% in the low energy region. The maximum deviation of longitudinal dose uniformity was 0.79% in the high energy region, and 2.22% in the low energy region. The monitor unit (MU) reproducibility factor was 0.106% and the maximum proportionality deviation was 0.67%. Conclusion:The dedicated nozzle of PBS has passed all the beam performance acceptance tests, which meet the requirements of all parameters, and the whole system yields relatively high accuracy, repeatability and good stability.