摘要目的 评价囊肿完整切除术与外囊切开内囊摘除术治疗肝囊型包虫病的有效性和安全性.方法 计算机检索Pubmed、EMBASE、MEDLINE、The Cochrane Library、中国生物医学文献数据库(CBM)、中国知网数据库、万方数据库、维普数据库、中文科技期刊全文数据库(全文版)和中国期刊全文数据库.收集2000年1月至2015年1月囊肿完整切除术与外囊切开内囊摘除术治疗肝囊型包虫病的随机或非随机同期对照试验.采用RevMan5.1统计软件进行Meta分析.结果 纳入10个随机或非随机对照试验,共2 123例患者.Meta分析结果显示:囊肿完整切除术治疗肝囊型包虫病较外囊切开内囊摘除术手术时间长[加权均数差(WMD)=25.11;95％ CI:16.18-34.05;P ＜0.05],住院天数短(WMD=-3.94;95％ CI:-7.57-0.32;P＜0.05),术后胆漏发生率低(OR =0.19;95％ CI:0.07-0.49;P ＜0.05),术后残腔感染发生率低(OR =0.08;95％ CI:0.04-0.15;P ＜0.05),术后复发率低(OR =0.10;95％ CI:0.05-0.18;P ＜0.05).结论 肝囊型包虫病囊肿完整切除术并发症少、复发率低,是目前治疗肝囊型包虫病的一种比较理想的根治疗法.

abstractsObjective To evaluate the effectiveness and safety of radical versus conservative surgery for hydatid liver cysts.Methods The Pubmed, EMBASE, MEDLINE, Cochrane Library, Chinese Biomedicine Database, CNKI, Wan Fang Databases, VIP Databases, Chinese scientific and technical journals full-text database and Chinese Journal of full text database were searched for randomized clinical trials or none-randomized clinical trials from January 2000 to January 2015.A Meta-analysis was performed with RevMan5.1.Results 10 studies with 2 123 patients were included into the final analysis.Meta-analysis demonstrated that the radical group was significantly longer in operation time [weighted mean difference (WMD) =25.11;95％ CI: 16.18-34.05;P ＜ 0.05], was significantly shorter in the length of hospital stay (WMD =-3.94;95％CI:-7.57-0.32;P ＜0.05), was significantly lower in the incidence of bile leak (OR =0.19;95％ CI: 0.07-0.49;P ＜ 0.05), was significantly lower in the incidence of residual cavity infection (OR =0.08;95 ％ CI: 0.04-0.15;P ＜ 0.05), and in the incidence of local recurrence (OR =0.10;95 ％ CI: 0.05-0.18;P ＜ 0.05) when compared with the conservative surgery group.Conclusions For hydatid liver cysts, radical surgical procedures had significantly lower rates of complications and recurrence.Thus, they are better treatments for hepatic cystic echinococcosis.