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目的 探讨术中MRI导航确定颌面部恶性肿瘤手术边界的可行性.方法 将65例颌面部肿瘤波及颅底的患者分为导航组(20例)与常规手术组(45例).导航组在术中MRI导航下行肿瘤切除术,根据MRI导航确定手术边界,并将颌面部恶性肿瘤患者首次手术切缘送病理检验,并与常规手术组比较.结果 导航组首次手术切缘阳性率[10％ (2/20)]明显低于常规手术组[44％(20/45)](P=0.007)；经统计学处理,导航组首次手术切缘阴性结果与组织病理学结果高度一致.结论 可移动高场强术中MRI导航可以准确判断颌面部肿瘤波及颅底的手术边界,与组织病理学诊断结果高度一致.

Objective To evaluate the feasibility of MRI navigation in identifing the safe surgical margin of the maxillofacial malignancy.Methods The pathology results of the surgical margin identified by the technique of MRI navigation form 20 patients with maxillofacial malignancy were compared with those of 45 patients with maxillofacial malignancy who underwent the routine operation without MRI navigation.Results There was no difference between the two groups of patients in age,sex,size of tumor,tumor stages,pathologic diagnosis (P ＞ 0.05).The negative rate of the surgical margin of the lesions treated by surgery with the technique of MRI navigation was significantly lower than that of the lesions treated without MRI navigation (P =0.007) and highly correspondent with the pathology results.Conclusions MRI navigation was helpful in identifying the safe surgical margin of the maxillofacial malignancy.