血清C反应蛋白对脑血管病预后的评估价值探讨
Three hundred patients with cerebrovascular disease within onset of 3 days were evaluated C-reaction protein level and cerebrovascular disease prognosis
对病程在3 d内的300例脑血管病患者入院时进行血清C反应蛋白(CRP)水平测定,根据血清CRP水平将患者分为A组(1.2±0.4)mg/L、B组(5.0±1.1)mg/L及C组(19.3±12.3)mg/L,同时应用临床神经功能缺损评分标准(SSS)和牛津残障评分(OHS)于治疗前和3个月后对患者重复评分,并将血清CRP水平与SSS及OHS进行相关性分析.结果患者血清CRP水平与人院时及治疗后3个月的SSS评分呈正相关(r分别为0.39、0.43,均P<0.01),与OHS评分呈正相关(r分别为0.40、0.42,均P<0.01).提示脑血管病发病后3 d内的血清CRP水平对患者的预后有一定评估价值.
更多Three hundred cerebrovascular disease (CVD) patients (disease onset <3 days) were evaluated for serum C-reactive protein (CRP) level at admission, and Scandinavian Stroke Scale (SSS) or Oxford Handicap Scale (OHS) at baseline and 3 months. Based on serum CRP levels, the participants were divided into group A [CRP(1.20 ±0.35)mg/L], group B[CRP(4.98 ± 1.08) mg/L] or group C[CRP (19.34±12.27)mg/L]. Our results showed that serum CRP level was positively correlated with SSS (r = 0.39 or0.43, both P<0.01) and OHS (r=0.40 or0.42, both P<0.01) at3 months. Thus, evaluating serum CRP level within 3 clays of disease onset might be helpful in predicting clinical outcomes of CVD patients.
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