两种胰岛素治疗方案对2型糖尿病患者骨折围手术期效果的比较
Comparison of two subcutaneous insulin regimens in type 2 diabetic patients with fractures during perioperative period
将234例2型糖尿病合并骨折患者按胰岛素的使用方案分为Ⅰ、Ⅱ两组,Ⅰ组162例,三餐前30 min皮下注射优泌林R,晚10:00皮下注射优泌林N;Ⅱ组72例,三餐前30 min皮下注射优泌林R,早餐前30 min和晚10:00两次皮下注射优泌林N.术前血糖达标时间Ⅰ组(9.1±3.3)d,Ⅱ组(7.0±2.6)d(P<0.01);Ⅱ组术后血糖控制更好;影响术前血糖达标时间的因素与入院空腹血糖、短效/中效胰岛素比例相关.Ⅱ组的胰岛素治疗方案对患者术前血糖达标更为有效.
更多We compare the results of two subcutaneous insulin regimens in type 2 diabetic patients with fractures during the perioperative period. In group Ⅰ 162 patients received regular insulin three times+ NPH insulin bedtime protocol; in group Ⅱ 72 patients received regular insulin three times + NPH insulin twice protocol. The difference of the time achieving satisfactory level of blood glucose (BG) and associated factors were analyzed, and the related complications were observed. The average time achieving satisfactory BG level was (9.1±3. 3) days and (7.0±2.6) days for group Ⅰ and Ⅱ respectively (P <0.05). There were no statistical differences in hypoglycemia, infection and thrombosis between two groups. Binary logistics regression showed that the time of achieving desired BG level was associated with blood glucose(BG) and the proportion of the regular insulin and the NPH. The results indicate that five times insulin injection method can shorten the time of achieving desired BG level and may be benefit to diabetic patients with fracture.
More- 浏览:322
- 被引:1
- 下载:116
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文