摘要在缺血缺氧性脑病患者的脑电监测中，全面性周期性放电是常被监测到的异常波形。当全面性周期性放电出现一些特征（如频率≥1.5 Hz或附加特征）时，提示患者癫痫发作风险高或预后不良。与常规脑电图相比，连续脑电图监测时间更长，因此这些波形检出率更高。目前，国内外学者对此类波形进行了研究，但在波形的意义方面存在争议。文中将对此类波形的定义、特征及在缺血缺氧性脑病患者中它们对判断患者预后和指导治疗等方面的意义作一综述。

abstractsIn the electroencephalography (EEG) monitoring of patients with hypoxic-ischemic encephalopathy, generalized periodic discharges are often monitored abnormal waveforms. When there are some features of generalized periodic discharges (e.g., frequency≥1.5 Hz or plus), it indicates that the patient is at high risk for seizures or has a poor prognosis. Compared with conventional EEG, the time of continuous EEG monitoring is longer, so the detection rate of these waveforms is higher. At present, scholars at home and abroad have studied these waveforms, but there is controversy about the significance of these waveforms. In this paper, the definition and characteristics of these waveforms and their significance in determining prognosis and guiding treatment in patients with hypoxic-ischemic encephalopathy are reviewed.