摘要目的 总结慢性胰腺炎的诊断和治疗经验。方法 回顾性分析1983～1999年8月收治的189例慢性胰腺炎病例资料。 结果 本组患者平均年龄48.4岁，高峰发病年龄为40～60岁，男∶女为2.1∶1。发病1年内确诊率51.3%，5年确诊率80.4%。CT和ERCP诊断阳性率较高，分别为71.9%和76.9%，PABA阳性率为69.7%。136例患者接受了手术治疗，术后并发症发生率为0.01%，1例患者因胰瘘、腹腔感染、败血症于术后第7天死亡。术后97.8%的患者主诉腹痛明显减轻。 结果 慢性胰腺炎早期诊断有一定困难，患者手术时机的掌握和手术方法的选择对于患者生存质量和疾病进程的控制至关重要。

abstractsTo summarize the experiences in the diagnosis and treatment ofchronic pancreatitis and to improve the management of this disease. Methods One hundred and eighty-nine patients with chronic pancreatitis admitted to our hospital from 1983 to August 1999 were reviewed, and the relevant clinical data were analyzed. Results The average age of the patients was 48 years old, with a male to female ratio of 2.1∶1. Around half of the patients were confirmed to have chronic pancreatitis by using multiple methods within a year. They accounted for four fifths of the patients finally diagnosed within the first five years. The positive rate of diagnosis for CT and ERCP was 71.9% and 76.9% respectively, and for PABA was 69.7%. Three fourths (136/189) of the patients with chronic pancreatitis were eventually subjected to surgical interventions. Surgical complications were rare; only one patient died of infection due to pancreatic leakage 7 days after operation. Most patients (98%) showed alleviation of symptoms, pain in particular, after surgical treatment. Conclusions Early diagnosis of chronic pancreatitis is considerably difficult. It is crucial to select various surgical strategies at a proper time point for chronic pancreatitis patients in order to change the natural course of the disease and further improve their life quality.