全身炎症反应综合征与急性胰腺炎合并高原红细胞增多症病情严重程度的关系
The relationship between systemic inflammatory response syndrome and severity of acute pancreatitis combined with plateau erythrocythemia
目的 探讨高原地区全身炎症反应综合征(SIRS)与急性胰腺炎合并高原红细胞增多症病情严重程度的关系.方法 回顾性分析2006年9月至2009年9月收治的40例符合急性胰腺炎合并高原红细胞增多症诊断患者及同期40例急性胰腺炎非高原红细胞增多症患者的临床资料,依据诊断标准分为高原红细胞增多症组和非高原红细胞增多症组.并将高原红细胞增多症组依据慢性健康状况Ⅱ评分分为轻症组和重症组.对患者有无SIRS、符合SIRS诊断标准数、SIRS诊断指标及急性胰腺炎合并高原红细胞增多症患者病情严重程度与SIRS持续时间的关系进行比较分析.结果 高原红细胞增多症组和非高原红细胞增多症组有无SIRS与符合2项SIRS诊断标准患者所占比例的差异有统计学意义(P<0.05);两组间SIRS各项诊断标准例数的差异有统计学意义(P<0.05);急性胰腺炎合并高原红细胞增多症和SIRS患者的病情严重程度与符合2~3项SIRS诊断标准患者所占比例的差异有统计学意义(P<0.05);急性胰腺炎合并高原红细胞增多症患者病情越严重,SIRS持续时间越长.结论 高原地区SIRS与急性胰腺炎合并高原红细胞增多症病情严重程度密切相关.
更多Objective To explore the relationship between systemic inflammatory response syndrome ( SIRS) and severity of acute pancreatitis combined with plateau erythrocythemia in the high altitude. Methods A retrospective analysis on the clinical data which involved acute pancreatitis combined with plateau erythrocythemia( n =40) and without plateau erythrocythemia( n =40) admitted from September 2006 to September 2009 was conducted. According to the unified standards, these cases were divided into plateau erythrocythemia group and no plateau erythrocythemia group. The patients in plateau erythrocythemia group were further divided into severe group and mild group according to scores of APACHE Ⅱ. The data was analyzed according to the patient with (or without) SIRS, SIRS's standard indicators, diagnostic parameter and relation of severity and duration of SIRS in acute pancreatitis combined with plateau erythrocythemia. Results There was significantly discrepancy between plateau erythrocythemia group and no plateau erythrocythemia group not only in the incidence of patients who developed SIRS,but also in two items of patients fulfilling or not fulfilling diagnostic criteria of SIRS( P < 0. 05 ). There was significant statistical difference in three items of diagnostic parameter of SIRS between plateau erythrocythemia group and no plateau erythrocythemia group (P <0. 05). Significant difference in two and three diagnostic parameter was found on severity of SIRS in acute pancreatitis combined with plateau erythrocythemia (P <0. 05). The more severity acute pancreatitis combined with plateau erythrocythemia was, the longer duration of SIRS was. Conclusion SIRS is highly correlated with the severity of SIRS in acute pancreatitis combined with plateau erythrocythemia in the high altitude.
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