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肾嗜酸细胞瘤26例临床特征分析

Analysis of clinical characteristics of renal oncocytoma: 26 cases report

摘要:

目的 探讨肾嗜酸细胞瘤的诊断、治疗和预后.方法 回顾性分析1999-2010年北京大学第一医院泌尿外科收治的26例肾嗜酸细胞瘤患者的临床特点、治疗方法、病理特征以及长期随访结果和预后.结果 患者平均年龄(55±14)岁,肿瘤平均最大径(4.1±1.3)cm,肿瘤平均体积(24±21)cm3.所有病例都接受外科手术治疗,其中5例行肾部分切除术,21例行肾根治性切除术.平均随访(47±34)个月(4~144个月),无复发、进展或死亡病例.结论 肾嗜酸细胞瘤是一种少见的肾脏良性肿瘤,临床表现及影像学检查均缺乏特异性.肾脏肿物穿刺活检是术前获得肾嗜酸细胞瘤病理诊断的惟一方法.肾嗜酸细胞瘤的预后良好,保留肾单位的手术或者射频消融、冷冻消融等微创治疗也许能取得满意效果.

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abstracts:

Objectives To investigate the diagnosis,therapy and prognosis of renal oncocytoma.Methods The data of 26 patients of renal oncocytoma in the department of urology of the Peking University First Hospital from 1999 to 2010 were collected.Retrospective analysis of renal oncocytoma clinical characteristics of patients including pathological characteristics and long term follow-up,treatment methods,and prognosis was undergone.Results The mean age of these patients was (55 ± 14) years,mean tumor size was (4.1 ± 1.3 ) cm,corresponding to a mean tumor volume of ( 24.0 ± 21.1 ) cm3.All of these cases were unilocular unilateral.All of these 26 patients received surgical treatment,5 cases accepted partial nephrectomy while the other cases accepted radical nephrectomy.After a median follow-up time was (47 ±34) months (range 4-144 months) for 25 patients who had been followed up,there was no disease recurrence,progression or death attributed to oncocytoma.Conclusions Renal oncocytoma is an uncommon tumor.It exhibits numerous features which are characteristic but not necessarily unique.Preoperative renal mass biopsy is the only way for prenephrectomy histologic diagnosis of oncocytoma.

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