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重视胆囊癌的规范化诊断和治疗

Attach importance to the standardized diagnosis and treatment of gallbladder carcinoma

摘要:

胆囊癌具有隐匿性、发展快、预后差等特点,改善其预后的关键在于早期诊断和规范化治疗。提高血液学和影像学诊断的灵敏度和准确性,及早发现特异性胆囊癌分子诊断靶标,有助于早期诊断和治疗。应重视术中再评估,选择恰当的手术方式。审慎开展腹腔镜下根治术,规范化切除癌灶和清扫区域性淋巴结,是提高R0根治切除率、改善预后的前提。未来以肿瘤学理念为指导,包括手术、化疗、靶向、免疫和生物治疗多种模式的综合治疗是胆囊癌治疗的发展趋势,但尚需进一步开展高质量的临床研究和跨学科合作。

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abstracts:

Gallbladder carcinoma,characterized by concealed onset,rapid development,and poor prognosis,needs to be valued by clinicians.The key to improving its prognosis remains early diagnosis and standardized therapy.Improving the sensitivity and accuracy of hematological and imaging diagnosis and early detection of specific molecular diagnostic targets for gallbladder cancer are helpful for early diagnosis and treatment.It is of great importance to emphasize on intraoperative reassessment and select the correct surgical procedures.It is the primary condition for increasing the R0 radical resection rate and improving the prognosis that prudentially carrying out laparoscopic radical resection and referring to standardized resection of cancer foci and regional lymph node removal.In the future,guided by concepts of oncology,comprehensive treatment of multiple modes,containing surgery,chemotherapy,targeted,immune and biological therapy,is the development trend of gallbladder cancer treatment,which requires high-quality clinical research and interdisciplinary cooperation.

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作者: 刘颖斌 陈炜
期刊: 《中华外科杂志》2021年59卷4期 249-254页 MEDLINEISTICPKUCSCD
栏目名称: 专家论坛
DOI: 10.3760/cma.j.cn112139-20210115-00031
发布时间: 2021-04-06
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