摘要颞叶癫痫在所有局灶性癫痫中发病率最高，具有病因学、症状学及电生理特征多样，进展为难治性癫痫率高的特点。手术是治疗难治性颞叶癫痫的有效手段，但传统方法通常难以对致痫区进行准确定位，立体脑电图技术为致痫区的准确定位提供了有效手段。基于立体脑电图的射频热凝和MRI引导的激光间质热疗，为手术风险高、难度大的难治性癫痫患者的外科治疗提供了精准、微创的新选择。

abstractsTemporal lobe epilepsy, with a variety of etiological, symptomatic, electrophysiological characteristics, has the highest incidence among all focal epilepsy, and a high rate of progression to refractory epilepsy. Surgery is an effective treatment, but traditional methods are usually difficult to accurately locate the epileptogenic zone, which may be resolved by stereotactic-electroencephalogram(SEEG) technique. Radiofrequency thermocoagulation and MRI-guided laser interstitial thermal therapy based on SEEG provide a new accurate and minimally invasive choice for refractory epilepsy patients with high surgical risk and difficulty.