室性早搏合并抑郁的发生率及危险因素分析
The incidence and risk factors of depression in Chinese patients with premature ventricular contractions without structural heart disease
目的 了解无器质性心脏病频发室性早搏(室早)患者合并抑郁的发生率及相关危险因素.方法 2005年10月至2007年10月在湖北、北京、广西、新疆、浙江5省市医院住院或门诊就诊,经筛查的无器质性心脏病频发室早患者1220名,填写Zung-SDS抑郁自评量表来评价患者是否合并抑郁;同时收集患者性别、年龄、文化程度、年收入、民族、社会支持、居住地、病程、24 h室早次数、24 h室早所占总心率的百分比、总胆固醇等11项指标,分别进行单因素和Logistic回归分析.结果 1144例患者完成测评(488例男性,656例女性),其中309名(27.01%)合并抑郁症,单因素分析显示中老年、低收入、教育程度低、少数民族、24 h室早所占总心率的百分数较多、病程长、社会支持差、农村居住地等的患者易发生抑郁(P<0.05).通过Logistic多变量逐步回归分析法显示:教育程度低(P=0.002)、农村居住地(P<0.001)、中老年(P<0.001)和24 h室早次数较多(P=0.005)是抑郁的独立危险因素.结论 在我国频发室早患者合并抑郁症并不少见,其中教育程度低、农村居住地、中老年和24 h室早次数较多是独立危险因素,室早与抑郁间的关系需进一步研究.
更多Objective The aim of this study is to study depression and potential risk factors in Chinese persons with premature ventricular contractions(PVCs)without structural heart diseases. Methods Zung self-rating depression scale(ZSDS) was used to scan depressive symptoms. Correlation between depression and sociodemographic,medical factors were analyzed by logistic regression. Results Of 1144 patients with PVCs [488 males,656 females,age(45±17) years, disease duration lmonth -21 years),a total of 309(27.01%)pa-tients were categorized as having depression. Percentage of depression in females was higher than that in males (28.20% vs. 25.41%,X2=1.106,P=0.313). Depression increased with age,income,education level,race,the percentage of PVCs of 24 h beats,disease duration,society support,settlement type. Multivariate logistic re-gression indicated that four variables-education level,settlement type,age and PVC count/24 h were significant-ly and independently related with depression(P<0.05). Conclusions In this Chinese population,depression in subjects with PVCs are frequent. The education level,the village settlement type, age and PVC count/24 h are independent risk factors for depression. Further research on the relationship between PVCs and depression in China is necessary.
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