摘要以伤残调整生命年（disability-adjusted life years，DALY)为指标汇总我国现有癌症疾病负担信息并进行分析。基于国际癌症研究署发布的2008年世界癌症发病和死亡报告（GLOBOCAN 2008)和2010年全球疾病负担研究（GBD 2010)项目平台，通过查询相关信息，对中国人群癌症相关DALY数据进行汇总、比较和分析，主要指标包括DALY，失能生存年（years lived with disability，YLD)等。两项目的主要差异在于关注病种范围和带入模型参数不同。GLOBOCAN 2008项目数据显示，我国男性肝癌的DALY负担居首位，为632万年，肺癌第2，为543万年；GBD 2010显示我国男性肝癌与肺癌的DALY年数分别为800和790万年。乳腺癌和大肠癌的YLD在我国人群DALY中的比例分别为26%(45万年)和12%(28万年)。我国肝癌DALY将超肺癌，建议尽早开展基于我国的系统失能权重研究，将DALY引入癌症负担评价体系。

abstractsDisability-adjusted life years(DALYs) has been increasingly used to estimate burden of disease worldwide. By giving a particular attention to DALYs, the objectives of the study were to review various data sources and to conduct an extended estimation on the burden of cancer in China. Based on the publications released by the GLOBOCAN 2008 program and the Global Burden of Disease 2010(GBD 2010) program, we reviewed the methodological information and gathered DALY data associated with burden of cancer in China, and then we extracted and summarized the data and conducted an extended analysis. From a methodological perspective, both of the programs applied the utility weights mainly from populations other than China. The data from GLOBOCAN 2008 suggests that liver cancer has replaced lung cancer and became the leading cancer in males in China when using DALY rather than mortality rate as the indicator (6.3 million and 5.4 million DALYs, respectively);although the ranking is different, data from the GBD 2010 project shows DALYs caused by liver cancer is comparable to that associated with lung cancer(7.9 million and 8.0 million, respectively). The years lived with disability(YLDs) comprised 26% and 12% of the total DALYs associated with breast cancer and colorectal cancer in China. Both projects suggest that liver cancer might have become or is becoming the leading contributor to males' DALYs in China. There are indications that, along with economic development, YLD will play a more important role in estimation of burden of cancer in China; it suggests that China should consider introducing DALY into the estimation system as early as possible. It also suggests that research on quality of life and utility associated with the major cancers in China need to be systematically conducted to facilitate more accurate DALY estimation.