不同年龄段健康成人肾脏表观扩散系数值的观察
Study of ADC value in healthy adults kidney of different age groups
目的 对不同年龄段健康成人进行肾脏MR扩散加权成像,探讨年龄因素对健康成人肾脏表观扩散系数(ADC)值的影响.方法 2012年6月至2013年8月,MRI检测100例健康成人,根据年龄的不同分为5个组(18~29岁,30~ 39岁,40~49岁,50~59岁和60~69岁),在3.0T磁共振扫描仪上行肾脏扩散加权成像(DWI)(b值采用800 s/mm2),测量各年龄段肾实质ADC值并进行统计学分析.结果 随着年龄的增长,肾实质ADC值有减小的趋势,5个年龄段肾实质ADC值依次为(2.07±0.10)×10-3 mm2/s、(2.06±0.12) ×10-3 mm2/s、(2.03±0.10)×10-3 mm2/s、(1.98±0.17)×10-3 mm2/s和(1.94±0.12)×10-3mm2/s,各组间差异有统计学意义(F=3.375,P<0.05).结论 (1)健康成人肾脏ADC值受年龄的影响,伴随年龄的增长,健康成人肾实质ADC值呈减小的趋势,尤其是40岁以上中老人ADC值的减小趋势更为明显;(2)临床应用中应注意年龄因素的影响,本研究所得数据可作为进一步研究的正常参考值.
更多Objective To evaluate the changes of ADC value on renal parenchyma at different age groups in healthy adults.Methods One hundred healthy adults were divided into five groups based on age:namely 18-29 years,30-39 years,40-49 years,50-59 years and 60-69 years.All adults underwent diffusion-weighted magnetic resonance(MR) imaging of the kidneys with b values of 800 s/mm2.ADC values of renal parenchyma were measured by the manufacturer's software.Results With the increasing of age,the renal parenchyma ADCs decrease.The ADCs of renal parenchyma in five age groups were (2.07 ± 0.10) ×10-3mm2/s,(2.06 ±0.12) × 10-3mm2/s,(2.03 ±0.10) × 10-3mm2/s,(1.98-±0.17) × 10-3mm2/s and (1.94 ±0.12) × 10-3mm2/s,which had statistically significant different(F =3.375,P < 0.05).Conclusion (1) The ADCs of renal parenchyma may be influenced by age,with the increasing of age,ADCs of normal kidney presented tenuous decreasing tendency especially the people aged ≥40 years;(2) in clinical application,we ought to pay attention to the influence of age factor.Income data of this study can be took as normal reference value in other more study.
More- 浏览:556
- 被引:5
- 下载:129
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文