摘要乙型肝炎相关慢加急性肝衰竭(HBV-ACLF)病死较高，早期准确评估其临床转归、采取有效的干预措施有助于延长患者生存时间。目前应用于HBV-ACLF预后的模型包括终末期肝病模型及其衍生评分，序贯器官衰竭评分及其衍生评分，亚太肝病学会慢加急性肝衰竭研究联盟评分，中国重型乙型肝炎研究组评分以及人工神经网络模型等，但对于HBV-ACLF特定人群，尚未就预后模型达成共识。本文总结了目前应用于HBV-ACLF患者的预后模型，为临床评估病情提供参考。

abstractsHBV related acute-on-chronic liver failure(HBV-ALCF) has high mortality. Early and precise assessment of clinical regression and effective interventions can help prolong the survival time of patients. Current models applied to the prognosis of HBV-ACLF include model for end-stage liver disease(MELD) and its derived score, sequential organ failure assessment and its derived score, Asian Pacific Association for the Study of Liver ACLF Research Consortium score, Chinese Group on the Study of Severe Hepatitis B score, and artificial neuron network model. However, there is no consensus prognostic model for the specific population with HBV-ACLF. In this paper, the prognostic models currently applied to patients with HBV-ACLF are summarized, so as to provide a reference for clinical assessment of the disease.