摘要克山病是一种原因不明的地方性心肌病,主要临床表现为心功能不全和心律失常.根据心功能状态和发病过程将克山病分为急型、亚急型、慢型和潜在型4种类型.本文就心力衰竭的治疗药物——利尿剂、神经激素拮抗剂、伊伐布雷定、正性肌力药、血管扩张剂等的药理机制以及用量进行详细阐述,以期为临床治疗提供依据.
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abstractsKeshan disease is an endemic cardiomyopathy of unclear cause.The major clinical manifestations are cardiac dysfunction and arrhythmia.Based on time course of onset and cardiac function of a suffering patient,Keshan disease is generally classified into four types:acute,sub-acute,chronic and latent types.This article elaborates on the pharmacological mechanisms and dosages of drug treatment for heart failure:diuretics,neurohormonal antagonists,ivabradine,positive inotropic drugs,vasodilators,etc,in order to provide basis for clinical treatment of chronic Keshan disease.
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