摘要目的:对照研究对比剂增强磁共振血管造影(CE-MRA)、T 1WI、三维薄层T 1WI序列在评价脑肿瘤血供的诊断效能，旨在改良脑肿瘤磁共振增强扫描方案。 方法:29例脑肿瘤患者注射对比剂后，依次扫描CE-MRA、T 1WI、三维薄层T 1WI序列，分别就"观察瘤实质强化"、"观察瘤体内小血管"、"观察瘤周小血管"的影像表现进行定性分级，应用McNemar卡方检验分析三种序列的诊断差异。 结果:⑴在"观察瘤实质强化"方面，CE-MRA、T 1WI、三维薄层T 1WI序列诊断达A1级(瘤体强化，图像清晰，与非强化区分界锐利)者分别为0例、8例(27.59%)、19例(65.52%)，三维薄层T 1WI序列诊断效能优于T 1WI序列( P<0.05)，T 1WI序列优于CE-MRA序列( P<0.05)。⑵在"观察瘤体内小血管"方面，CE-MRA、T 1WI、三维薄层T 1WI序列诊断达B1级(可清晰观察瘤体内小血管，并能追踪上级血管)者分别为8例(27.59%)、5例(17.24%)、16例(55.17%)，三维薄层T 1WI序列诊断效能优于T 1WI序列与CE-MRA序列( P<0.05)。⑶在"观察瘤周小血管"方面，CE-MRA、T 1WI、三维薄层T 1WI序列诊断达C1级(可清晰显示瘤体与邻近血管关系)者分别为18例(62.07%)、5例(17.24%)、14例(48.28%)，CE-MRA、三维薄层T 1WI序列诊断效能优于T 1WI序列( P<0.05)。 结论:联合三维薄层T 1WI与CE-MRA序列可全面评估瘤体血供，对脑肿瘤定位、定性、指导治疗具有重要意义。

abstractsObjective:To evaluate the diagnostic efficiency of contrast-enhanced magnetic resonance angiography (CE-MRA), T 1WI and three-dimensional thin-layer T 1WI sequences (3D-T 1WI) in evaluating the blood supply of brain tumors, so as to improve the enhanced magnetic resonance imaging (MRI) scanning scheme of brain tumors. Methods:After the contrast agent was injected, 29 patients with brain tumors were scanned with CE-MRA, T 1WI and 3D-T 1WI. The imaging manifestations of " observing the enhancement of tumor substance" , " observing the small vessels in the tumor body" and " observing the small vessels around the tumor" were qualitatively classified, and the diagnostic differences of the three sequences were analyzed by McNemar test. Results:⑴ In the aspect of " observing the contrast medium in the tumor body" , CE-MRA, T 1WI and 3D-T 1WI sequences diagnosed as grade A1 were 0 cases, 8 cases (27.59%) and 19 cases (65.52%) respectively. The diagnostic efficiency of 3D-T 1WI sequences was better than that of T 1WI sequence ( P<0.05), and T 1WI sequence was better than that of CE-MRA sequence ( P<0.05). ⑵ In the aspect of " observing the small vessels in the tumor" , CE-MRA, T 1WI and 3D-T 1WI sequences diagnosed as grade B1 were 8 cases (27.59%), 5 cases (17.24%) and 16 cases (55.17%), respectively. The diagnostic efficiency of 3D-T 1WI was better than that of T 1WI and CE-MRA ( P<0.05). ⑶ In the aspect of " observing the small vessels around the tumor" , CE-MRA, T 1WI and 3D-T 1WI sequences diagnosed as grade C1 were 18 cases(62.07%), 5 cases (17.24%) and 14 cases (48.28%) respectively. The diagnostic efficiency of CE-MRA and 3D-T 1WI wre better than that of T 1WI ( P<0.05). Conclusions:The combination of 3D-T 1WI and CE-MRA sequence can comprehensively evaluate the blood supply of the tumor, which is of great significance for the localization, characterization and treatment of brain tumors.