换一批摘要自身免疫性胶质纤维酸性蛋白星形胶质细胞病是一种可治的中枢神经系统自身免疫性炎性疾病，以脑膜、脑、脊髓和视神经等受累为主要表现，磁共振成像可见脑室旁线样放射状强化和（或）脊髓长节段受累伴中央强化病灶，脑活体组织检查提示小血管周围炎症伴小胶质细胞活化，对类固醇激素治疗敏感。胶质纤维酸性蛋白抗体被认为是本病的特异性生物标志物。
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abstractsAutoimmune glial fibrillary acidic protein astrocytopathy is a curable autoimmune inflammatory disease of the central nervous system. Meninges, brain, spinal cord and optic nerve are mainly involved. Radial paraventricular enhancement and/or long segment lesions of spinal cord with central enhancement can be seen on magnetic resonance imaging. Brain biopsy shows perivascular inflammation with microglia activation. The disease is sensitive to steroid therapy. Glial fibrillary acidic protein antibody is considered as a specific biomarker of the disease.
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DOI
10.3760/cma.j.cn113694-20190603-00329
发布时间
2026-09-08（万方平台首次上网日期，不代表论文的发表时间）
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