摘要目的：了解中国女性宫颈人乳头瘤病毒（HPV）感染状况及型别分布特征。方法以PubMed、中国知网、万方数据库为检索源，系统检索2004—2013年公开发表的中英文文献，摘录相关信息。分别将全国以及7个地理区域 HPV 感染研究的统计数据进行数据分析。结果符合纳入标准的数据覆盖全国所有省份和地区，样本量共计661658例，年龄范围16~87岁。共纳入文献245篇，我国女性人群宫颈 HPV 感染率为25.0％，感染率最高的6个高危型别依次为 HPV16、HPV52、HPV58、HPV18、HPV33和 HPV31。我国所有地区以 HPV16为主要感染型别，HPV52和 HPV58的检出率明显高于 HPV18，而 HPV35和 HPV45检出率较低。结论 HPV 感染型别分布有明显地域性，我国的统计数据与世界范围的统计数据有明显差异。我国7个地理区域间感染型别分布也有差异。

abstractsObjective To analyze the genotype distribution of human papillomavirus( HPV) strains and their epidemiological characteristics in cervixes of Chinese females. Methods Pertinent litera-tures published during 2004 to 2013 were screened from PubMed,China National Knowledge Infrastructure (CNKI)and Wanfang database for data analysis. Results There were 245 studies screened out for the me-ta-analysis. A total of 661 658 cases met the inclusion criteria,ranging from 16 to 87 years old. All prov-inces and territories of China were covered by the data. The overall rate of HPV infection in cervix was 25. 0% among Chinese females. The predominant high risk genotype of human papillomavirus strains was HPV16,followed by HPV52,HPV58,HPV18,HPV33 and HPV31. HPV52 and HPV58 genotypes were more prevalent than HPV18 genotype. HPV35 and HPV45 genotypes were less popular. Conclusion The study suggested that the HPV infection showed obvious regional differences in genotypes. The genotype dis-tribution of HPV infection in China was different from that in other regions of the world. There were differ-ences with genotype distribution of HPV strains among seven geographic regions of China.