Rapamycin and MPA, but not CsA, impair human NK cell cytotoxicity due to differential effects on NK cell phenotype.
第一作者:
D N,Eissens
第一单位:
Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
作者:
医学主题词
细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);环孢菌素(Cyclosporine);细胞毒性, 免疫(Cytotoxicity, Immunologic);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);免疫抑制剂(Immunosuppressive Agents);干扰素γ(Interferon-gamma);杀伤细胞, 天然(Killer Cells, Natural);霉酚酸(Mycophenolic Acid);NK细胞凝集素样受体亚家族C(NK Cell Lectin-Like Receptor Subfamily C);表型(Phenotype);受体, 自然杀伤细胞(Receptors, Natural Killer Cell);西罗莫司(Sirolimus);组织分布(Tissue Distribution)
DOI
10.1111/j.1600-6143.2010.03242.x
PMID
20883533
发布时间
2023-01-24
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