Crystal structure of reduced and of oxidized peroxiredoxin IV enzyme reveals a stable oxidized decamer and a non-disulfide-bonded intermediate in the catalytic cycle.
                第一作者:
                
                        
Zhenbo,Cao
                        
                
            
            
                第一单位:
                
                        
                            Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, United Kingdom.
                            
                        
                
            
                    
                作者:
                
                
            
            
        
			主题词
			催化作用(Catalysis);催化域(Catalytic Domain);色谱法(Chromatography);结晶学, X线(Crystallography, X-Ray);半胱氨酸(Cysteine);二硫化物类(Disulfides);大肠杆菌(Escherichia coli);人类(Humans);过氧化氢(Hydrogen Peroxide);动力学(Kinetics);模型, 化学(Models, Chemical);模型, 分子(Models, Molecular);分子构象(Molecular Conformation);突变(Mutation);氧化性应激(Oxidative Stress);氧(Oxygen);硫氧还原蛋白过氧化物酶类(Peroxiredoxins)
		
        		
			DOI
			10.1074/jbc.M111.298810
		
        		
			PMID
			21994946
		
        		
			发布时间
			2024-04-17
		
    - 浏览18
 
                
            The Journal of biological chemistry
42257-42266页
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