Molecular biology and clinical features of hereditary non-polyposis colorectal cancer.

摘要:

Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited disease associated with germ-line mutations in mismatch repair genes and microsatellite instability. This article reviews the molecular biology and clinical pathology of HNPCC.

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期刊:
《Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae》 2012年34卷3期293-7页
DOI: 10.3881/j.issn.1000-503X.2012.03.021
PMID: 22776665
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