肺Castleman病临床研究新进展
New progress in clinical research of pulmonary Castleman's disease
Castleman病为一种较少见、原因不明的不典型淋巴组织增殖性疾病,又称血管滤泡性淋巴组织增生、巨大淋巴结病或血管瘤性淋巴错构瘤.此病至今病因不明,其病理形态多样化,临床表现和预后高度异质性,易被误诊为多种临床常见病,应引起临床医师重视.确诊有赖于淋巴结活检和病理学检查,目前临床治疗方式主要是手术和化疗.本文就肺Castleman病的分类和临床病理特点、病因和发病机制、影像学特征、临床表现、诊断和临床常见误诊疾病及误诊原因分析、治疗等方面进行分析、整理和归纳总结,为该疾病的诊断与治疗提供参考.
更多Castleman's disease (CD) is a rare and unknown atypical lymphoid tissue proliferative disease,also known as follicular lymphoid tissue hyperplasia,giant lymphadenopathy or hemangiomatous lymphatic hamartoma.It was first reported and named by Castleman in 1956.Up to now,the etiology of this disease is unknown,its pathological morphology is diverse,its clinical manifestations and prognosis are highly heterogeneous,and it is easy to be misdiagnosed as a variety of common clinical diseases,which should be paid attention by clinicians.The diagnosis depends on lymph node biopsy and pathological examination.At present,the main clinical treatment is surgery and chemotherapy.The classification,clinicopathological characteristics,etiology and pathogenesis,imaging features,clinical manifestations,diagnosis and treatment of pulmonary Castleman's disease were analyzed,sorted out and summarized in this paper,in order to provide reference for the diagnosis and treatment of this disease.
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