人巨细胞病毒疫苗接种的目标人群
The ideal target population for cytomegalovirus vaccine
人巨细胞病毒( HCMV)的感染普遍且通常无症状,但却有很多个体是HCMV感染的高危人群.HCMV疫苗的接种能够使感染后发病率降低已在国内外达成共识,然而不管是疫苗的临床试验还是合法疫苗的最终临床应用,HCMV疫苗的目标人群的确立都举足轻重.此文就HCMV疫苗研究现状及目标人群的确立进行综述.
更多Although infection with human cytomegalovirus(HCMV) is ubiquitous and usually asymptomatic,there are individuals at high risk for serious HCMV disease.It is widely acknowledged that vaccination of HCMV vaccine will be benefit in reducing the incidence after HCMV infection.However,it is of great importance to find out the target population of HCMV vaccination,not only in clinical trial,but also in the ultimate clinical application of the vaccine.In this article,the research situation and target popultion of HCMV vaccines are reviewed.
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