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反常性痤疮是一种发生在毛囊和皮脂腺的慢性复发性炎症性皮肤病,常合并聚合性痤疮、头部脓肿性穿凿性毛囊周围炎,主要临床表现为顶泌汗腺部位的脓肿、窦道及瘢痕形成.该病病因复杂,目前尚无明确原因,其发病可呈家族聚集性.近年来,该病临床表现的分型,伴发风湿性疾病、代谢综合征、炎症性肠病等疾病有了进展.希望提高对伴发疾病及并发症的警惕性,给患者提供个性化的综合治疗方案,提高患者生活质量.

Acne inversa(AI) is a chronic recurrent inflammatory skin disease involving hair follicles and sebaceous glands. It is usually complicated by acne conglobata and perifolliculitis capitis abscedens et suffodiens. The main clinical manifestations are abscesses, sinuses, and scars in areas bearing apocrine sweat glands. The pathogenesis of AI is complicated and remains unclear so far, and its occurrence shows familial aggregation.Recently,great progress has been made in researches on clinical phenotypes and comorbidities of AI, such as rheumatic diseases, metabolic syndrome, inflammatory bowel diseases, and so on. The authors summarize its phenotypes and comorbidities, in hope to enhance understanding of this entity, so as to offer patients individualized systemic treatment strategies, and increase their quality of life.