换一批
换一批Aberrant DNA Methylation in Cutaneous Squamous Cell Carcinoma
摘要：
IntroductionCutaneous squamous cell carcinoma (CSCC) is the secondmost common non-melanoma skin cancer after basal cell carcinoma, accounting for 20％ of all cutaneous malignancies. CSCC originates from epidermal keratinocytes or adnexal structures such as eccrine glands or pilosebaceous units.1 According to several studies focused on Caucasian populations in Europe, the USA and Australia, about 15– 35 per 100,000 individuals are diagnosed with CSCC each year, and the incidence of CSCC is expected to increase by 2％–4％ per year.2 The incidence of primary CSCC has increased by 50％–300％ globally, especially amongst Caucasian populations in New Zealand, Australia, and North America over the last 3 decades.
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作者单位：
Department of Dermatology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003 China
[1]
West China School of Medicine, Sichuan University, Chengdu, Sichan 610041 China
[2]
Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China
[3]
期刊：
《国际皮肤性病学杂志（英文）》2019年2卷4期 227-232页
MEDLINEISTIC
栏目名称：
Review Articles
DOI：
10.1097/JD9.0000000000000054
发布时间：
2020-01-11
基金项目：
Our work was supported by grants from the Chinese Academy Medical Sciences Initiative for Innovative Medicine
National Natural Science Foundation of China
Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs
Jiangsu provincial SixTalent Peaks
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