摘要脓毒症是机体对感染的反应失调而导致危及生命的器官功能障碍,是当今危重病医学所面临的焦点和难点问题.目前世界范围内儿童脓毒症的发生率仍居高不下,若治疗不及时可发展成脓毒性休克、多器官功能障碍综合征,严重威胁人类健康.因此脓毒症的早期识别、诊断、治疗对降低病死率有重要意义.而生物标记物在脓毒症的早期诊断、病情及预后判断,疗效评估中发挥重要作用.本文就近年来脓毒症的生物标记物进行总结.

abstractsSepsis is defined as life-threatening organ dysfunction caused by the disorder of the body′s response to infection.Sepsis is the focus of critical illness medicine and difficult problems nowadays.At pres-ent,the incidence of sepsis in children is still high around the world.If the treatment is not timely,sepsis can develop into septic shock,multiple organ dysfunction syndrome,which is a serious threat to human health. Therefore,the early identification,diagnosis and treatment of sepsis is important for reducing mortality.And the biomarkers play an important role in the early diagnosis of sepsis,pathogenetic condition and prognosis as well as efficacy evaluation.This article summarized the biomarkers of sepsis in recent years.