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目的：探讨持续性静脉血液滤过（CVVH）在大面积深度烧伤患者治疗中的应用。方法选择2010年10月至2014年4月武警后勤学院附属医院烧伤整形科收治的各种原因造成的特重度烧伤患者30例，在常规烧伤治疗的基础上，行CVVH治疗，并于治疗前后不同时间点监测体温、心率、平均动脉压（MAP）、呼吸等生命体征，取外周血检测细胞因子、电解质、肾功能。结果 CVVH治疗后患者体温、心率、MAP及呼吸改善，外周血肿瘤坏死因子α（TNF-α）、白细胞介素-6（IL-6）及白细胞介素-8（IL-8）浓度下降，Na+、K+、尿素氮（BUN）、肌酐（SCr）值下降，差异均有统计学意义（P<0.05）。结论 CVVH能够清除患者体内炎症介质、清除肌酐、尿素氮，纠正肾功能衰竭，改善预后。

ObjectiveA propective study to approach the effect of the continuous venous vell-hemafiltration in theraping deep burned patients.MethodsFrom October 2010 to April 2014,30 cases due to various reasons in severe burn patients were treated with the continuous venous vell-hemafiltration in the Affiliated Hospital of Logistics University of Chinese People's Armed Police Forces. Before and after treatment at different time points of monitoring temperature, heart rate, mean arterial pressure (MAP), breathing life signs, peripheral blood detection of cytokines, electrolyte, renal function.ResultsTo improve the patient body temperature, heart rate, and respiration of MAP after CVVH treatment, peripheral blood tumor necrosis factor alpha (TNF- alpha), interleukin -6 (IL-6) and interleukin -8 (IL-8) concentration decreased, Na+, K+, blood urea nitrogen (BUN), creatinine (SCr) value decreased, the difference was significant statistical significance (P<0.05).ConclusionContinuous venous vell-hemafiltration is a ideal treatment for deep burned patients.