摘要手术是原发局限性胃肠间质瘤(GIST)唯一可能治愈的手段.但术后复发的风险持续存在,评估复发风险对指导是否需要进行靶向药物辅助治疗和判断预后十分关键.虽然对原发局限性GIST完全切除后的复发风险评估变量和风险等级等已确定,但无论是F/NIH共识、AFIP标准、改良NIH标准等,还是近年来尝试应用的数学计算模型风险识别方法包括Jason S Gold风险列线图、Rossi列线图和Joensuu高热线图等,均缺乏长期的、无选择偏倚的大型临床研究验证,无法提供较为准确的复发风险概率.

abstractsSurgery is the only possible cure protocol of gastrointestinal stromal tumor(GIST).But the risk of recurrence exists constantly.Risk assessment of relapse is very important to guide the targeted adjuvant therapy and predict the prognosis.Although the variables and grading in the risk assessment of recurrence after complete resection of primary local GIST have been identified,but either the F/NIH consensus,AFIP standards,modified NIH standards,or risk identification methods attempted to apply mathemafical calculation model in recent years,including Jason S Gold risk nomogram,Rossi nomogram,Joensuu high Hotline Dengjun,are short of long-term,large-scale clinical trials withou selection bias.Therefore,recurrence risk probability cannot be predicted accurately.