急性冠脉综合征伴发焦虑抑郁情绪患者生活质量的研究
Quality of life in patients with acute coronary syndrome combined anxiety and depressive symptoms
目的 研究急性冠脉综合征(acute coronary syndrome,ACS)患者伴随焦虑抑郁情绪时的生活质量(quality of life,QOL).方法 使用综合性医院情绪测量表(HADS)和健康状况调查问卷(SF-36)分别对688例ACS住院患者进行情绪测量及QOL评估.根据HADS评分结果,将入组的ACS患者分为焦虑组、抑郁组、焦虑抑郁组以及非焦虑非抑郁组.结果 焦虑组、抑郁组、焦虑抑郁组及非焦虑抑郁组QOL评分依次为:生理机能(56.92±23.92)分;(52.91±32.24)分;(53.03±27.34)分;(62.51±27.15)分、生理职能(31.08±38.49)分;(34.97±40.44)分;(23.86±33.60)分;(45.40±43.57)分、躯体疼痛(55.14±23.86)分;(55.78±29.45)分;(49.39±24.51)分;(65.39±24.98)分、一般健康状况(40.16±20.20)分;(39.74±21.39)分;(35.22±19.66)分;(51.09±21.98)分、精力(53.52±18.39)分;(55.81±21.60)分;(48.02±21.48)分;(66.68±23.13)分、社会功能(62.04±26.78)分;(62.99±28.31)分;(54.13±27.58)分;(75.83±24.90)分、情感职能(42.33±43.12)分;(51.64±44.65)分;(30.00±37.85)分;(58.69±44.83)分、精神健康(65.39±18.62)分;(72.11±20.46)分;(58.01±20.29)分;(82.69±16.43)分,组间比较差异有显著性(P<0.05).结论 ACS患者伴发焦虑抑郁情绪时QOL显著降低,以伴发焦虑抑郁双重障碍的ACS患者的QOL最低.
更多Objective To assess the quality of life(QOL) in patients with acute coronary syndrome(ACS) combined depressive symptoms and(or) anxiety.Methodes Hospital anxiety depressive symptoms scales(HADS) and short-form-36 health survey(SF-36,Chinese version) were completed by 688 hospitalized patients with ACS.Results According to HADS scores,the study population were divided into four groups:anxiety group,depressive symptoms group,depressive symptoms combined anxiety group,non-anxiety or depressive symptoms group.QOL of each group had statistical differences.The score of physical functioning:56.92±23.92,52.91±32.24,53.03±27.34,62.51±27.15.The score of social functioning:31.08±38.49,34.97±40.44,23.86±33.60,45.40±43.57.The score of bodily pain:55.14±23.86,55.78±29.45,49.39±24.51,65.39±24.98.The score of general health:40.16±20.20,39.74±21.39,35.22±19.66,51.09±21.98.The score of vitality:53.52±18.39,55.81±21.60,48.02±21.48,66.68±23.13.The score of role-physical:62.04±26.78,62.99±28.31,54.13±27.58,75.83±24.90.The score of role-emotional 42.33±43.12,51.64±44.65,30.00±37.85,58.69±44.83.The score of mental health:65.39±18.62,72.11±20.46,58.01±20.29,82.69±16.43(P<0.05).Conclusion For ACS patients,symptoms of anxiety and depressive symptoms were associated with significant worsening of QOL.
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