摘要目的 探讨应变率成像(SRI)技术在高血压患者左室局部早期舒张功能中的应用价值.方法 50例原发性高血压患者分为左室心肌正常组31例(高血压Ⅰ组)和左室心肌肥厚组19例(高血压Ⅱ组),同时选取对照组(健康人)25例.分别对3组进行传统的脉冲二尖瓣口血流(PW)及瓣环平面6个不同位点的SRI和多普勒组织(DTI)检测并对比分析.结果 高血压组6个不同位点的SRe均降低、SRa均升高,与对照组相比差异具有统计学意义(P<0.05);SRe值与患者病程发展呈负相关(r=-0.89,P<0.05),而SRa在6个不同位点均有升高,与病程呈正相关(r=0.97,P<0.05),SRe/SRa<1位点检出率Ⅱ组>Ⅰ组>对照组(P<0.05).高血压组3种检测方法比较,SRI检测SRe/SRa<1的总检出率(88%)大于DTI的Em/Am<1(79.67%)及PW的E/A<1(60%),尤其在Ⅰ组中表现更为明显,检出率为SRI>DTI>PW(P<0.05).结论 SRI优于传统PW和DTI检测法,特别是对高血压患者左室局部早期舒张功能异常的判断更为敏感、更为准确.

abstractsObjective To explore the value of strain rate imaging (SRI) technology in the diagnosis of hypertension patient with re-gional left ventricular early diastolic dysfunction. Methods 50 essential hypertension patients were divided into hypertension Group Ⅰ and Group Ⅱ, including 31 patients with normal left ventricular and 19 patients with left ventricular hypertrophy. 25 healthy people were used as the control group. SRI was done in the six different basal myocardial segments and the parameters of SRI were compared with that of Doppler tissue imaging (DTI) and pulse Doppler (PW). Results In the hypertension group, SRe of the six different basal myocardial segments was lower than that in the control group (P<0.05), but (SRa) of hypertension group was higher (P<0.05). SRe was negatively correlated with the patients'illness development (r=-0.89, P<0.05), but SRa was positively correlated (r=0.97, P<0.05). And the SRe/SRa<1 detection rate of Group Ⅱ was higher than that in Group Ⅰ, and the ratio in the control group was lowest(P<0.05). Total detection rate of SRI (88%) was higher than Em/Am <1 of DTI (79.67%) and E/A < 1 of PW(60%), and these changes were more obvious in Group Ⅰ. SRI was higher than DTT and PW (P<0.05). Conclusion Compared with traditional technology and methods, SRI could pro-vide more accurate diagnoses to hypertension patient with regional left ventricular early diastolic dysfunction.