3.0 T高分辨率MR血管壁成像对大动脉炎活动性判断的价值
Role of 3.0 T MR vessel wall imaging for identifying the activity of Takayasu arteritis
目的 探讨3.0 T高分辨率MR血管壁成像对大动脉炎活动性判断的价值.方法 26例确诊为大动脉炎的患者(根据Lupi-Herrea分类,为Ⅰ和Ⅲ型,均累及主动脉弓及其主要大分支)接受了颈部及上胸部MR血管壁成像,其中处于病情活动期16例,非活动期10例.分析并比较了2组患者受累动脉管壁的MRI表现特征.采用X~2检验对2组患者的血管壁形态进行统计学分析.结果 所有受累动脉的血管壁均有不同程度的环形增厚.活动期组患者的管壁厚度较非活动期组患者增厚明显[分别为(3.8±0.2)和(2.5±0.8) mm];比较2组增厚的血管壁形态,管壁呈多环征(分别为75/80和18/50)、内壁明显强化(分别为50/80和19/50)、血管外界模糊不清(分别为55/80和18/50)等征象,差异均有统计学意义(X~2值分别为50.39、7.41、13.40,P值均<0.01).结论 大动脉炎高分辨率MR血管壁成像的主要征象是管壁增厚及信号改变,3.0 T MR血管壁成像能精细观察血管壁的形态学变化,对大动脉炎的活动性判断具有重要价值.
更多Objective To analyze and explore the value of 3 T high resolution magnetic resonance vessel wall imaging for identifying the activity of Takayasu arteritis. Methods Twenty-six consecutive patients with Takayasu arteritis underwent 3.0 T high resolution MR vessel wall imaging on supraortic vessels (according to the classification of Lupi-Herrea , type Ⅰ and Ⅲ were included). Sixteen patients were in active phase and 10 in inactive phase based on the Kerr criteria. The MR vessel wall imaging appearances of Takayasu arteritis were compared between the active phase and inactive phase cases. Results Wall thickening was demonstrated in all involved arteries. There were statistically significant differences between active phase and inactive phase cases in MR appearances including multi-ring thickening of vessel wall (75/80 and 18/50), arterial inner wail enhancement (50/80 and 19/50), obscurity of perivascular fat (55/80 and 18/50,X<'2>=50.39,7.41,13.40,P<0.01). There was also a statistically significant difference in the thickness of carotid artery wall between the two groups [ (3.8±0.2) mm vs (2.5±0.8) mm]. Conclusion 3 T high resolution MR vessel wall imaging is valuable for identifying the activity of Takayasu arteritis.
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