免疫球蛋白G4相关肝胆疾病的诊断和鉴别诊断
Diagnosis and differential diagnosis of immunoglobulin G4-related hepatobiliary disease
免疫球蛋白G4相关疾病(IgG4-RD)是一类具有共同特定病理学、血清学和临床特征的免疫介导性疾病.IgG4-RD可能包含炎性假瘤、IgG4相关自身免疫性肝炎、I型自身免疫性胰腺炎累及肝脏三种临床类型.IgG4相关硬化性胆管炎罕见单独发病,多与I型自身免疫性胰腺炎同时存在,需要与原发性硬化性胆管炎相鉴别.
更多Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated disease that share common pathologic, serologic and clinical features. IgG4-RD may include inflammatory pseudotumor, IgG4-related autoimmune hepatitis, and type 1 autoimmune pancreatitis mainly involving liver and clinically classified into three types. IgG4-related sclerosing cholangitis is a rare disease. It is frequently present in association with type 1 autoimmune pancreatitis, so it needs to be distinguishing from primary sclerosing cholangitis.
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