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目的 了解天津地区健康体检人群的血尿酸水平,以及本地区高尿酸血症(HUA)的患病率及其影响因素.方法 对28 661例健康体检者检测血尿酸、空腹血糖,三酰甘油、总胆固醇、体重指数、血压,分析血尿酸水平及HUA检出率,以及HUA组与正常组的代谢综合征相关因素比较.结果 天津市健康体检人群HUA检出率11.3%,其中男性HUA检出率为15.2%,女性6.3%.血尿酸平均值男性为(349±73)μmol/L,女性为(256±59)μmol/L.男性血尿酸峰值在30～39岁组,女性峰值在≥70岁组,男性明显高于女性(P＜0.01).HUA组的血糖、三酰甘油、总胆固醇水平均高于正常组,超重/肥胖、高血糖、高血脂、高血压检出率均高于正常组.结论 HUA高发于中年男性.血尿酸与代谢相关因素密切相关,应对健康体检人群进行HUA相关知识的普及,减少HUA的患病率.

Objective To investigate blood uric acid levels in health check-up receivers in Tianjin City. Methods Blood uric acid levels in 28 661 health check-up participants were tested and the incidence of hyperuricaemia was analyzed. Blood pressure, body mass index, blood sugar, cholesterol and triglyceride were measured and compared. Results The average level of blood uric acid was (349±73 ) μ mol/L in male,and (256±59) μmol/L in female. The peak value in male was found in the 30 to 39 years old group,while in female the age was increased to 70 years old. The incidence of hyperuricaemia was higher in male ( 15. 2% vs 6. 3% ,P＜0.01). The level of blood sugar,triglycerides and total cholesterol was higher in the hyperuricaemia group. Also in the hyperuricaemia group, the incidence of overweight/obesity,hyperglycaemia, hyperlipidemia and hypertension was higher. Conclusions The incidence of hyperuricaemia in routine health check-up individuals in Tianjin City could be 11.3%. Blood uric acid may be significantly associated with metabolism.