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自适应光学(AO)是一种通过降低光学像差的影响以提高光学系统性能的技术,与扫描激光检眼镜结合(AOSLO)应用于眼科可以矫正人眼屈光系统的像差,从而极大地提高成像的分辨率和成像质量.AOSLO能够在活体视网膜上观察到细胞水平的微观结构如光感受器、神经纤维、血管壁细胞等,从而可以发现疾病的早期改变,同时在疾病的随访中亦可观察视网膜微观结构的改变.目前,由于AOSLO内部固有的技术缺陷,限制了其在临床的广泛应用.随着AO技术的不断进步,相关软件功能的进一步完善,系统将变得更加成熟,必将在科研和临床中发挥越来越重要的作用.

Adaptive optics (AO) is a technique to improve the performance of optical systems by reducing the influence of optical aberrations.Combined with scanning laser ophthalmoscope (AOSLO),the aberration of human refractive system can be corrected.Thus,the resolution and quality of imaging can be greatly improved to the cellular level in vivo retina (such as photoreceptor,nerve fibers,vascular parietal cell),therefore the earlier changes of the diseases can be detected.At the same time,microstructure changes of retinal can also be observed during the follow-up of the disease.Due to inherent technical defects of AOSLO,its wide application in clinical practice is limited.With the continuous progress of AO technology and the further improvement of related software functions,the function of the system will become more stronger and will play a more and more important role in scientific research and clinic.