您的账号已在其他设备登录,您当前账号已强迫下线,
如非您本人操作,建议您在会员中心进行密码修改

确定

肾癌肾单纯性和根治性切除的疗效及安全性比较

A comparative study of nephrectomy and radical nephrectomy for renal cell carcinoma

摘要:

目的 比较肾癌单纯性肾切除与根治性肾切除的疗效及安全性.方法 对134例无淋巴和远处转移临床资料基本相同的肾癌患者,选取69例肾癌患者行肾癌单纯性肾切除,另65例行根治性肾切除,总结两组患者临床资料,并对手术时间、手术出血量、术后禁食时间、术后住院时间、肿瘤复发情况、肿瘤转移、无瘤生存时间、生存率、并发症发生等指标进行比较.结果 单纯组手术时间60~135 min,出血量70~100 ml,胸腹膜损伤4例;术后禁食时间6~24 h,术后住院时间5~8 d;所有患者均获得肿瘤分期;随访5~15年,死亡4例(非癌死亡2例),肾上腺转移1例,复发2例.根治组手术时间105~185 min,术中出血150~2000 ml,胸腹膜损伤3例;术后禁食时间12~90 h,术后住院时间8~12 d;所有患者获得肿瘤分期;随访5~15年,死亡4例(非癌死亡1例),复发1例.两组手术并发症、肿瘤复发转移、无瘤生存时间差异无统计学意义(P>0.05),单纯组手术时间、手术出血量、术后禁食时间、术后住院时问明显少于根治组(P<0.05).结论 对无淋巴和远处转移的肾癌,单纯性肾切除是一种高效、安全的治疗方法,在手术时间和术后住院时间、减少创伤及减少出血方面比根治术更优越.

更多
abstracts:

Objective To compare the clinical efficacy and safety of nephrectomy versus radical nephrectomy for renal cell carcinoma(RCC).Methods A total of 134 patients with renal carcinoma without metastasis in lymphatic system and distant sites were recruited.In random.69 cases of renal cell carcinoma were elected for nephrectomy and the others radical nephrectomy.The operating time,blood loss,fasting time,postoperative hospital stay,information of tumor recurrence and metastasis,survival time without tumor,survival rate and perioperative complication were compared between two groups.Results In cases of nephrectomy,the operating time ranged from 60-135 minutes and blood loss 70-100 mL In 4 cases,membrana pleuroperitonealis was damaged. The fasting time ranged from 6-24 hours and postoperative hospital stay 5-8 days;the staging of all 69 cases was detected;follow-up studies ranged from 5-15 years,finding 1 case tumor metastasis in adrenal body and 1 case recurrent tumor in csaes of radical nephrectomy,operating time ranged from 105-185 minutes and blood loss 150-2000 ml.Membrana pleuroperitonealis was breached in 3 cases.The fasting time ranged from 12-90 hours and postoperative hospital stay 8-12 days.The staging of all 65 cases was detected.Follow-up studies of 5-15 years revealed 1 case of tumor metastasis in brain and 1 case of recurrent tumor.There was no significant difference in perioperative complication.tumor recurrence,tumor metastasis and survival time without tumor between those two groups(P>0.05).The blood loss,operating time,fasting and postoperative hospital stay were less than that in radical nephrectomy group(P<0.05).Conclusion In patients without metastasis in lymphatic system and distant sites,nephrectomy is both effective and safe.It has the advantages of a short operating time,a short postoperative hospital stay and less damage and blood loss than radical nephrectomy.

More
作者: 俞洪元 [1] 陈柏康 [1] 张显军 [1] 李飞平 [1] 王天济 [1] 丁崇标 [1] 吴松江 [1] 卢子文 [1] 柯莽 [1] 张文刚 [1]
期刊: 《中华医学杂志》2010年90卷16期 1120-1122页 MEDLINEISTICPKUCSCDCA
分类号: R73
栏目名称: 临床研究|%Clinical Research Articles
DOI: 10.3760/cma.j.issn.0376-2491.2010.16.012
发布时间: 2010-06-29
  • 浏览:129
  • 下载:18

加载中!

相似文献

  • 中文期刊
  • 外文期刊
  • 学位论文
  • 会议论文

加载中!

加载中!

加载中!

加载中!