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目的 评价微等离子体射频联合曲安奈德治疗增生性瘢痕的临床效果及安全性.方法 选取41例增生性瘢痕患者,以微等离子体射频联合曲安奈德对皮损行5次治疗,采用临床显效、有效和无效三级标准对疗效进行评价.随机选取5例患者于治疗前及5次治疗后1年留取瘢痕标本,观察瘢痕组织的病理学改变.结果 41例患者中28例显效,11例有效,2例无效,总有效率为95.12％.患者瘢痕体积、厚度均减小,随访期内无复发及并发症发生.组织学研究显示治疗后瘢痕真皮层变薄,成纤维细胞数减少,胶原纤维排列趋于整齐、疏松.结论 微等离子体射频联合曲安奈德治疗增生性瘢痕疗效确切、安全性高.

Objective To evaluate the efficacy and safety of micro-plasma radiofrequency (MPR) combined with triamcinolone acetonide in the treatment of hypertrophic scar.Methods 41 patients with hyperplastic scar were enrolled.The scars were treated by micro-plasma RF combined with triamcinolone acetonide.A total of 5 treatments were performed.The curative effect was evaluated as markedly effective,improved and uneffective.The histological study was performed on 5 patients before and after all the treatments.Results A total of 41 patients were followed up,28 cases were markedly effective,11 cases improved and only 2 patient was uneffctive.The overall effective rate was 95.12 ％.Significant reduction in the thickness and texture of the scar were achieved,and no side effect was observed.Histological studies showed,after all the treatments,that the number of fibroblasts were reduced and collagen fibers arranged more orderly and loosy.Conclusions MPR combined with triamcinolone acetonide is a safe and highly effective treatment for hypertrophic scar.